Peptide Active Data Details
Basic Peptide Information
DICL ID
DICL_Pep_00281
Ion Channel
Neuronal acetylcholine receptor subunit alpha-9/alpha-10
Peptide Function
Inhibitor
Gene Name
Chrna9/Chrna10
Activity Data (nM)
IC50
4.61 nM
Ki
Not available
EC50
Not available
Kd
Not available
Biologically Active
Not specified
Sequence Information
Peptide Sequence
TCRSSGRYCRSPYDRRRRYCRRITDACV
Peptide UniProt Accession
UniParc
UPI00085DE742
Peptide Synonyms/Alias
[CHEMBL4553407; GeXIVA[1;4]; GLXC-27609; BDBM50520487; TC(1)RSSGRYC(2)RSPYDRRRRYC(2)RRITDAC(1)V; Thr-Cys(1)-Arg-Ser-Ser-Gly-Arg-Tyr-Cys(2)-Arg-Ser-Pro-Tyr-Asp-Arg-Arg-Arg-Arg-Tyr-Cys(2)-Arg-Arg-Ile-Thr-Asp-Ala-Cys(1)-Val]
Peptide Species
Conus generalis (General cone)
Peptide Name
Alpha-conotoxin GeXIVA
CAS Number
Not available
Experimental Conditions
pH
pH 9.6
Holding Potential (mV)
Not specified
Temperature
25 ± 1 °C
Test Method
Binding assay
Test Species
Not specified
Binding Information
Binding Site
Not specified
Binding Site Residue
Not specified
Ion Channel Information
Gene Abbreviation (ABB)
nAChRs
Ion Channel UniProt Accession
Source Organism
Rattus norvegicus (Rat)
References & Disease Information
Disease
Not specified
PubChem CID
Not available
URL
Not available
PMID
Patent
Not available